TRANSURETHRAL REMOVAL FOR SUCCESSFUL DIAGNOSIS OF BLADDER MALAKOPLAKIA: A RARE CASE REPORT
Introduction: Malakoplakia is a rare granulomatous inflammatory disorder of infectious etiology that most often involves the urinary tract. Because it is so rare and can present in several different ways, malakoplakia poses a difficult diagnostic challenge.
Case report: We report an unusual clinical case of bladder malakoplakia in a 75-year –old man. He presented to urologist with hematuria, burning on urination, urinary urgency and frequency. Cystoscopy evaluation revealed yellowish polypoid lesion with easy bleeding in the trigone of the bladder. Microscopic evaluation showed acidophilic, foamy histiocytes (Von Hansemann cells) admixed with Michaelis-Gutmann inclusions. The final postoperative diagnosis was malakoplakia of the bladder.
In conlusion, we reported a case of malakoplakia of the bladder diagnosed with minimally invasive approach by transurethral resection. It is important to be aware of this rare granulomatous disease as accurate diagnosis with antibiotic treatment can prevent possible complications.
Badillo LGF, Aguileria BI, Prada CS, Pedroza LVR, Lanzabal JDS. Renal malakoplakia. A case report. Rev Colomb Radiol.2018;29(3):4987-91.
Kim SH, Choi YS, Kim ES, Lee K, Lee JH, Kang HG et al. Bladder malakoplakia mimicking bladder cancer.Korean J Med.2017;92(5):476-9.
Dong H, Dawes S, Philip J, Caudhri S, Subramonian K. Malakoplakia of the urogenital tract. Urol Case Rep. 2014 ;3(1):6-8.
Wong SHL, Yeung VHW, Lee WK , Lee YK, Chan MTY, Cheng CH et al. Malakoplakia of the urinary tract: A benign disease with a possible malignant outcome. J Case Rep.2016;6:254-8.
Niknejad N., Nili F., Shirkhoda M. Malakoplakia in association with adenocarcinoma of sygmoid colon: A case report. Iran J Pathol. 2019;14(3):258-60.
Kyriakou G, Gialeli E, Vryzaki E, Koumoundourou D, Glentis A, Georgiou S. Malakoplakia of the skin:overview of a rare clinical entity. Dermatol Online J.2019;25(6):232-7.
Fudaba H, Ooba H, Abe T, Kamida T, Wakabayashi Y, Fujiki M, et al. An adult case of cerebral malakoplakia successfully cured by treatment with antibiotics, bethanechol and ascorbic acid. J Neurol Sci.2014;342(1):192-6.
Lee SL, Teo JK, Lim SK, Salkade HP, Mancer K. Coexistence of malakoplakia and papillary urothelial carcinoma of the urinary bladder. Int J Surg Pathol. 2015; 23(7):575-8.
Patnayak R, Reddy MK, Subramanian S, Jena A, Ravisankar G, Dandu RS. An unusual case of bilateral hydroureteronephrosis caused by uretero-vesico malakoplakia in a young male: a case report and review of the literature. Cases J.2009;2(1):7527.
Papilomata E, Agarwala N, Ioannnis M, Vorous MI, Balaxis AD, Filindris NT, Chalambous NS et al. Malakoplakia of genitourinary tract: A report of 3 cases. Urotoday Int J.2010;3(4). Available from: http://dx.doi.org/10.3834/uij.1944-5784.2010.08.12
Yousef GM, Naghibi B, Hamodat MM. Malakoplakia outside the urinary tract. Arch Pathol Lab Med. 2007;131(2):297-300.
Hina S, Hasan A, Iqbal N, Shabbir MU, Sheikh AAE. Malakoplakia of the urinary bladder and unilateral ureter. J Coll Physicians Surg Pak. 2019;29 (6):582-4.
- There are currently no refbacks.
Copyright (c) 2020 Ivo Vujicik
This work is licensed under a Creative Commons Attribution 4.0 International License.