THE OXYBUTYNIN ABUSE IN ADOLESCENT CASE

Omer Kardas, Burcu Kardas

Abstract


Oxybutynin is one of the most commonly prescribed drugs in overactive bladder treatment. Because of its lipophilic structure, it crosses the blood-brain barrier and causes cognitive side effects in the central nervous system. Abuse of the drug is due to its hallucinogenic effect. In terms of substance use disorder, adolescents are one of the groups at risk. In addition to well-known addictive substances, drugs which have sedative, anticholinergic-antimuscarinic, stimulant properties and prescribed for any treatment also can be abused in adolescents with substance abuse. In this article, it is aimed to raise awareness of physicians and health workers about oxybutynin abuse because of the pharmacodynamic characteristics of the drug and its effects on the central nervous system. The health professionals should therefore prescribe this drug with more attention and follow-up those patients.


Keywords


oxybutynin, adolescent, addiction, abuse

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References


Dwyer J, La Grange CA. Oxybutynin. In: Stat Pearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018. Available from: https: // www. ncbi. nlm. nih. gov / books/NBK499985/

Jirschele K, Sand PK. Oxybutynin: past, present, and future. Int Urogynecol J. 2013; 24(4):595-604.

Herberg K. Safety in everyday situations and street traffic with the use of medication for incontinence. New investigations into the safety and potential of urological anticholinergic drugs. Med Welt. 1999; 50(50):217–22.

Ruxton K, Woodman RJ, Mangoni AA. Drugs with anticholinergic effects and cognitive impairment, falls and all-cause mortality in older adults: A systematic review and meta-analysis. Br J Clin Pharmacol. 2015; 80(2):209-20.

Can SS. Oksibutinin kötüye kullanımı llan bir olgu. T. Psikiyatri Dergisi. 2015; 26(2): 147-8.

Gurol DT. Madde Bağımlılığı Açısından Riskli Adolesanlar. İ.Ü. Cerrahpaşa Tıp Fakültesi Sürekli Tıp Eğitimi Etkinlikleri. Adolesan Sağlığı II. Sempozyum Dizisi. 2008; 63: 65-8.

Steınberg L. Ergenlik. Çok F. (Çeviren). Ankara: İmge Kitabevi, 2007.

Ögel K, Erol B. Çocuklarda Sigara, Alkol ve Madde Bağımlılığı “Çocuğum Madde Bağımlısı Olmasın”. 1. Baskı. Ankara: Morpa Kültür Yayınları, 2005.

Lee SS, Humphreys KL, Flory K, Liu R, Glass K. Prospective association of childhood attention-deficit/hyperactivity disorder (ADHD) and substance use and abuse/dependence: a meta-analytic review. Clin Psychol Rev. 2011; 31(3):328–41.

Başay Ö, Yüncü Z, Kabukçu Başay B, Öztürk Ö, Aydın C. Alkol-madde kullanım bozuklukları olan ergenlerin kişilik özellikleri. Anadolu Psikiyatri Derg. 2016; 17(2):127-35.

Hayatbakhsh R, Mamun AA, Williams GM, O'Callaghan MJ, Najman JM.. Early childhood predictors of early onset of smoking: a birth prospective study. Addict Behav.2013; 38(10):2513–9.

Arslan D, Cansiz MA, Tufa, AE, Öztürk Y. Oxybutynin abuse in an adolescent leading to psychotic symptoms. Anatolian Psychiatry J. 2017; 18(3):301-2.

Kınık MF, Dönder F, Duymaz MK, Karakaya, I.Addiction of Oxybutynin: An Adolescent Case Report. J Addict Res The. 2015; 6(228):2.

Kumsar Akkişi N, Okay İT, Dilbaz N. Oksibütinin Kötüye Kullanımı ve Bağımlılığı; İki Olgu Sunumu. Klinik Psikofarmakoloji Bulteni. 2009;19: 123-4.

Aydın O, Aydın PU. Oksibutinin kullanımının yol açtığı psikotik bozukluk. Anadolu Psikiyatri Derg. 2016; 17(4):333.

Gulsun M, Pinar M, Sabanci U. Psychotic disorder induced by oxybutynin. Clin drug investig. 2006; 26(10): 603-6.

Balasar M, Çiçekçi F. Oxybutynin addiction amongst prisoners: two case reports/Mahkumlar arasinda oxibutinin bagimliligi: Iki olgu sunumu. Anadolu Psikiyatri Dergisi, 2016; 17(3): 77-80.




DOI: http://dx.doi.org/10.24125/sanamed.v14i1.300

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