ACUTE RENAL FAILURE IN THE NEWBORNS HOSPITALIZED AT THE INTENSIVE CARE UNIT, UNIVERSITY CLINICAL CENTRE TUZLA

Evlijana Zulic, Devleta Hadzic

Abstract


Introduction: Reasons for acute renal failure in hospitalized infants were sepsis, hypovolemia, asphyxia, respiratory distress syndrome, surgical interventions and congenital heart defects.
The aim of this study was to determine the frequency and and main etiologies, and early outcome of neonatal acute renal failure.
Materials and Methods: At Intensive Care Unit, Clinical Center Tuzla, from 15. 01. 2013 to 15. 01. 2015 in 21 newborn was diagnosed renal failure, based on the amount of excreted urine and serum creatinine.
Results: The prevalence of renal failure was 6.84%, with a higher incidence of female. 33.3% of infants were term neonates. Oliguria was diagnosed in 71.4% of newborns. Sepsis was the most common predisposing factor for the development of renal failure, associated with high mortality. Other causes of renal failure were perinatal hypoxia, RDS, surgical interventions and congenital heart defects. There was a positive correlation between the gestational age of the newborn and serum creatinine.
Discussion: Early prevention of risk factors with rapid diagnosis and effective treatment, can affect further outcome of acute renal failure in infants.
Key words: acute kidney injury, newborns, intensive care unit.


Full Text:

PDF

References


Andreoli SP. Acute renal failure in the newborn. Semin Perinatol. 2004; 28(2): 112–23.

Momtaz HE, Sabzehei MK, Rasuli B, Torabian S. The main etiologies of acute kidney injury in the newborns hospitalized in the neonatal intensive care unit. J Clin Neonatol. 2014; 3(2): 99–102.

Gouyon JB, Guignard JP. Management of acute renal failure in newborns. Pediatr Nephrol. 2000; 14(10–11): 1037–44.

Youssef D, Abd-Elrahman H, Shehab MM, Abd-Elrheem M. Incidence of acute kidney injury in the neonatal intensive care unit. Saudi J Kidney Dis Transpl. 2015; 26(1): 67–72.

Kleinman LI, Stewart CL, Kaskel FJ. Renal disease in the newborn. In: Edelman CM Jr, editor. Pediatric Kidney Disease. 2nd ed. Boston: Little, Brown and Co; 1992. p. 1043.

Csaicsich D, Russo-Schlaff N, Messerschmidt A, Weninger M, Pollak A, Aufricht C. Renal failure, comorbidity and mortality in preterm infants. Wien Klin Wochenschr. 2008; 120(5–6): 153–7.

Andreoli SP. Management of acute kidney injury in children: a guide for pediatricians.Paediatr Drugs. 2008; 10(6): 379–90.

Ricci Z, Ronco C. Neonatal RIFLE. Nephrology Dialysis Transplantation. 2013; 28(9): 2211–4.

Mortazavi F, Hosseinpour Sakha S, Nejati N. Acute kidney failure in neonatal period. Iran J Kidney Dis. 2009; 3(3): 136–40.

Subramanian S, Agarwal R, Deorari AK, Paul VK, Bagga A. Acute renal failure in neonates. Indian J Pediatr. 2008; 75(4): 385–91.

Libório AB, Branco KM, Torres de Melo Bezerra C. Acute Kidney Injury in Neonates: From Urine Output to New Biomarkers. Biomed Res Int. 2014; 2014: 601568.

Nouri S, Mahdhaoui N, Beizig S, et al. Acute renal failure in full term neonates with perinatal asphyxia. Prospective study of 87 cases. Arch Pediatr. 2008; 15(3): 229–35.

Pejovi} B, Peco-Anti} A, Dunji} R. Acute oliguric renal failure in hypoxic neonates born at full term. Srp Arh Celok Lek. 2002; 130(11–12): 367–70.

Askenazi DJ, Ambalavanan N,Goldstein SL. Acute kidney injury in critically ill newborns: What do we know? What do we need to learn? Pediatr Nephrol. 2009; 24(2): 265–74.

Durkan AM, Alexander RT. Acute kidney injury post neonatal asphyxia. J Pediatr. 2011; 158(2 Suppl): e29–e33.

Hornik CP, Krawczeski CD, Zappitelli M, et al. Serum brain natriuretic peptide and risk of acute kidney injury after cardiac operations in children.Ann Thorac Surg. 2014; 97(6): 2142–7.

Aggarwal A, Kumar P, Chowdhary G, Majumdar S, Narang A. Evaluation of renal functions in asphyxiated newborns. J Trop Pediatr. 2005; 51(5): 295–9




DOI: http://dx.doi.org/10.24125/sanamed.v10i1.16

Refbacks

  • There are currently no refbacks.


Copyright (c) 2016 SANAMED

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.